AMNIOQUICK® offers a convenient solution to obstetricians and midwives for accurate diagnosis of PROM. AMNIOQUICK® is a rapid test based on the detection in vaginal samples of IGFBP-1 (Insulin-Like Growth Factor Binding Protein-1), which is found in high concentration in amniotic fluid. A pair of monoclonal antibodies anti-IGFBP-1 is used for the detection of IGFBP-1. One is immobilized on the nitrocellulose membrane at the level of the test line: it corresponds to the capture antibody. Another one is labelled with colloidal gold for the subsequent manifestation. During the sample migration, IGFBP-1, if present in the sample, will form antigen antibody complexes with the labelled antibodies. These complexes will be caught by the capture antibodies on the test line, creating one purple coloured line generated by gold nanoparticles. The presence of a purple internal control line in the upper part of the membrane indicates that the result is valid and that the followed procedure is correct. AMNIOQUICK® can be used from the early stages of pregnancy to near term women. It is an easy-to-use rapid test that allows better management of PROM.

  • Complete kit with ready to use components
  • Simple one-step test
  • Rapid results (10-15 minutes)
  • High analytical sensitivity and specificity
  • Non- invasive method
  • Highly sensitive monoclonal antibody (IGFBP-1)
  • Visual reading by presence or absence of colour bands
  • IVD/CE


Size Product code Regulatory Status
10 tests 0524_K10 IVD/CE



  1.  The American College of Obstetricians and Gynecologists: practice bulletin clinical management guidelines for obstetrician-gynecologists, number 139 October 2013
  2.  Beckman et al, Hospital versus outpatient care for preterm pre-labour rupture of membranes, Australian and New Zealand Journal of Obstetrics and Gynaecology 2013; 53: 119–124
  3.  Rutanen et al, Comment on: Guidelines for the management of spontaneous preterm labor: identification of spontaneous preterm labor, diagnosis of preterm premature rupture of membranes, and preventive tools for preterm birth, The Journal of Maternal-Fetal and Neonatal Medicine, 2012; 25(5): 546–549

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